Activate Autophagy & Burn Fat Fast With This 1 Food (Easier Than Fasting) | Dr. Dominic D’Agostino



Dr. Dominic D’Agostino is a tenured Associate Professor at the University of South Florida whose research focuses on ketogenic nutrition, metabolism, neuroscience, and metabolic therapies.

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00:00 – Intro
01:31 – The 3-Day Sardine Fast Explained
06:09 – What a Sardine Fast Does to Your Body
11:48 – When Autophagy Starts During a Sardine Fast
15:24 – The Best Sardine Brands & How to Make Them Taste Better
19:00 – Which Fish Give You Similar Benefits to Sardines?
22:22 – Why Sardines Are So Filling & Nutrient Dense
26:29 – What to Expect During a 3-Day Sardine Fast
32:02 – How to Enhance a Sardine Fast
37:41 – Do You Really Need More Fiber for Gut Health?
49:59 – Ketone Salts vs Esters & 1,3-Butanediol
01:05:40 – Salt, Insulin Resistance & Electrolytes on Keto
01:10:18 – Creatine, MCT Oil & Supplements Without Gut Issues
01:17:00 – What to Look for in a Ketone Supplement
01:21:10 – The 4 Types of Ketones & What They Do
01:30:48 – Understanding Ketone Supplements
01:37:23 – How to Use Ketones for Better Mental Performance
01:53:57 – How the Body Uses Ketones
01:56:39 – What to Know Before a Sardine Fast

Show notes:

Connect with Dr. Dominic D’Agostino:
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YouTube –
Instagram –
Metabolic Health Initiative –

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Disclaimer: The opinions expressed in this video are those of the guest and are presented for informational purposes only. This content is not medical advice. Please consult your healthcare provider regarding any health-related decisions.

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41 Comments

  1. If you enjoy this, please click the LIKE button to let me know you want more like it 👍 And if you haven't already, do me a quick favour and hit the SUBSCRIBE button to join the growing community (it's simple and free). Thanks for the support 🙏 I appreciate you! -Jesse 💙

  2. @18 min I love the apple cider vinegar and often add 1 Tbs butter and warm for 30 seconds in the microwave. Almost got rid of case of chicken of the sea but will keep now and just rinse it. Thought a YouTube said it wasn’t healthy due to source. I’ll trust D’Agostino first.

  3. citare il termine “digiuno” è molto in voga, tuttavia non giustifica l’errore di usarlo in modo scorretto.
    Quando ci si alimenta NON è digiuno ma “dieta” mentre solo quando non ci si alimenta si può chiamare “ digiuno” che può essere secco, senza acqua o idrico se si beve acqua .. tutto qui.

  4. Excellent!!! I like how much i learnt from this video. I must re-listen to it to truly register all the significance of what i heard. A lot of information and a lot to digest & process……..Thank You Dr.D'Agostino & Chappus@ 😂🎉❤

  5. El ayuno no es para todos, sobre todo en menopausia donde disminuye tu masa muscular, y la dieta de sardinas no es sostenible, la gente más longeva del mundo, es omnivora y come alimentos integrales

  6. Love listening to Dom and no matter how many times i have heard his interviews you always learn something new to help tweak a ketogenic low carb or carnivore adjacent way of eating

  7. A “sardine enthusiast”😂
    Not making fun, it just sounds funny. I’ve heard the word enthusiast paired with many things, but not sardines.
    I’ve been a sardine enthusiast for years as well. Excellent video here!

  8. insulin must be low in order to trigger deep autophagy… protein must be low and stomach empty… no nutrients coming in…. What triggers insulin? 15+ grams protein, carbs and/or stress..(physical or mental)…

  9. I have been diagnosed with Vitamin A toxicity. My liver was huge and I had an MRI and blood work which was fine. They had to do a biopsy of my liver and found it's toxic with Vitamin A. I've eaten a tin of Cod livers and the oil maybe once a month over 2 years but earlier I took a multi vitamin with Vitamin A daily for 20 years. Years ago during the juicing fad I drank carrot juice frequently. All of this built up and isn't going to detox at my age now. The doctors said it can take 20 years of low A diet. Just watch out. Eggs and butter has Vitamin A. In nature foods are cyclical with the seasons. Today everything is available at the store all year long.

  10. Soy de la Ciudad de México Diabético desde junio de este año empecé con dolores en la espalda fui al fisio terapeuta y me comento que estaba perdiendo masa muscular he tenido mi glucosa por arriba de 200 hasta 345 y lo menos 215, 226 y no bajaba mas ni con medicamento hago ejercicio nado 2 veces por semana y camino mucho 7mil a 10mil pasos como aparentemente sano jugos verdes por la mañana comida casera por la tarde me dijo que tal vez necesite ya insulina ya había visto videos pero me llamaron la atención los del ayuno y no quiero que me inyecten insulina me propuse desde el 1 de julio ayunar empecé 17horas para hoy la hago hasta de 20, 22 horas y dieta ketoo nada de carbohidratos después de casi 3 meses mi glucosa bajo empecé por abajo de 200 y de repente arriba el 1er mes, (al cumplir 30 días llegue a 87 y se me olvido tomar ese día la sitagliptina y la deje de tomar) después de 2 meses abajo de 200 ya no subía al cumplir 60 días llegue lo mas bajo a 74 y a los 80 días hasta 64 me siento bien con animo y fuerzas he documentado en mi canal mi proceso quiero revertir la diabetes hice la dieta de las sardina 3 dias y como de vez en cuando sardina me siento muy bien voy a cumplir los 3 meses y me hare exámenes haber que me dicen los doc gracias por este contenido gracias a eso me apoyo por que aqui en MX dicen que estoy loco

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