Vitamin D – Vitamin D2, Vitamin D3 and Calcitriol | Doctor Mike Hansen
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🩺 Ask Doctor Hansen:
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What are all of these things?
They refer to the various forms of Vitamin D in our bodies or in the food we eat. For example, vitamin D3 is also known as cholecalciferol; this is made naturally by the body in response to sunlight. Vitamin D2 is also known as Ergocalciferol and comes from plants. Vitamin D supplements come in the form of either Vitamin D3 or Vitamin D2. If you prefer, calcitriol or 1,25-dihydroxy vitamin D is the active form of vitamin D in our body. When sunlight contains ultraviolet B (UVB) radiation, and when it hits your skin cells, it turns 7-dehydrocholesterol into vitamin D3, meaning cholecalciferol. Vitamin D3, in turn, binds to vitamin D-binding protein (VDBP) and is transported to the liver, where it gets converted to calcidiol, aka 25-hydroxyvitamin D.
Calcidiol is the storage form of vitamin D in the body. Calcidiol is later converted to the active form of vitamin D in the body, meaning calcitriol, or 1,25-dihydroxy vitamin D. This conversion of calcidiol into calcitriol mainly occurs in the kidney. But it also takes place in different tissues and cells of the immune system, such as lymph nodes and alveolar macrophages. And not only in alveolar macrophages but the alveoli themselves.
Vitamin D3 is only found naturally in a few different food sources, mainly fatty fish, like cod, swordfish, tuna, and salmon. Milk doesn’t naturally contain vitamin D3, but it has been fortified with it for almost 100 years now. But other dairy products made from milk like cheese and ice cream aren’t typically fortified with vitamin D and contain only small amounts. So to meet the RDA of 800 IU, older adults would have to drink about 4 cups of fortified milk per day. Vitamin D3 mainly comes from sunlight, though, not food. But the skin’s vitamin D production depends on several factors, only some of which you have control.
Depending on the season, where you live, where you travel, the time of day, the clothing you wear, and the umbrella you use, all of these factors determine how much UVB light hits your skin. The sun’s rays are most direct between 10 a.m. and 3 p.m. However, the farther you live from the equator, the less UVB radiation you receive. People who live north of about 37° latitude can’t make any vitamin D from sunlight from November to March.
Why is this the case?
During the winter months, the earth tilts away from the sun, ultimately leading to fewer sun rays hitting the earth. Having darker skin means less UVB absorption, which means less vitamin D3 production. Also, as we age, our bodies become less efficient at converting UVB light into vitamin D3. This is why older people and darker skin people are more prone to have lower vitamin D levels. Many older people have reduced exposure to sunlight for different reasons and may not be getting enough vitamin D in their diet to make matters worse.
Vitamin D signals the intestines to absorb calcium into the bloodstream.
This happens even if you have enough calcium in your diet. Besides strengthening bones, vitamin D helps reduce fractures in the elderly by preventing muscle deterioration and reducing the chances of falling.
The official definition of a vitamin deficiency means that specific health problems arise due to not having enough of a particular nutrient. True vitamin D deficiency in children causes rickets, a bone disease where the legs become bowed. This is rare in the United States. Vitamin D deficiency in adults can lead to osteomalacia and osteoporosis, leading to bone fractures. So what if you don’t have deficiency per se, but you have less-than-ideal levels of a specific vitamin? Well, this can increase your risk of various health issues, even though they are not solely responsible for these problems. This is what we call “Insufficiency.”
Most medical societies consider someone with vitamin D insufficiency if their level is between 12 to 20 ng/mL (30 to 50 nmol/L), and Vitamin D deficiency is less than 12 ng/mL (30 nmol/L). Most experts consider normal levels to be above 20 and less than 50 ng/ml. Most people in the United States have values around 20 ng/ml.
But having too high levels can cause other health issues. In one study, levels above 32 ng/ml resulted in people getting less quality sleep. The risk of vitamin D toxicity typically occurs at levels over 100 ng/mL in adults who also ingest substantial calcium amounts. Vitamin D toxicity, whether it’s from vitamin D3 or vitamin D2, generally occurs after inappropriate use of vitamin D. It’s essential to avoid excess vitamin D in pregnancy because that can cause calcium levels to rise to the point of causing seizures in the mother and developmental problems in the baby.
#vitamind #d3
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What about Calcifediol? Is it good for us?
The milk here in the UK is not safe. I now have oat milk.
how to quickly reduce the level of vitamin d in the blood, besides stopping taking the supplement? is there a cure
Why would you take calcium for longer time or High UI doses of Vit D even in calcium deficiency what if body respiration has gone down which prevent nutrients absorption including required calcium hence remaining nutrients in blood specially calcium get utilized by bone now due to low nutrients absorption less calcium and other minerals in blood however calcium supplement is not the answer even though calcium phosphate(Vit-D/D3) pushes itself in blood due to fast reacting chemical combination which does increase calcium but also increases cyst formation but body remains depleted of other minerals hence improving body respiration back to normal should be the goal for better uptake of required nutrients from food digestion.(Like why take Vit D(D3)/Omega 3 in oil form when it's not absorbed in high respiration side(Asymmetrical Person) causes more issues on low oxidation side)
The information is simple and self explanatory.❤
I don’t know any plant that contains vit d .. oily fish / eggs maybe .. but not plants .
You need magnesium to convert d3 to the active form. When supplementing it will increase absorption of calcium from food . You need k2 to transport that calcium to where it should be in the bones / teeth.. otherwise some will deposit in organs and blood vessels or even joints causing all sorts of issues. So d3 / k2 and magnesium important to have enough of.
Mackerel twice a week, the only fish I eat😅
cholecalciferol is a rat poison??
how much is vitamen d3 and where to buy?
Thank you very informative information. My vitamin D is low so my doctor prescribed me Ergocalciferol but its vitamin D2. But i have been taking it. But everybody's saying vitamin D3 is better so should i tell my doctor to switch me to vitamin D3
Excellent…
"discussion with a doctor" ???? about vitamin D ?? hahahahahahaahahaha
Show me one study that proves cholecalciferol is in fact vitamin d produced by our bodies during sun exposure … show me one !!! I can show you numerous studies of vitamin d poisoning of any living being on earth ! You have been fooled- these doctors pushers have no clue what they are talking and have iq lower than a chicken . They only can parrot each other without a gram of their own research
10:55 NORMAL… Funny guy.
Can anyone tell me what about alfacalcidol form of Vitamin D?
Also what abour combo of D3 +k2 (100mcg)
After years of using and learning about vitamin D from various sources, I really appreciate how clearly you’ve broken down the difference between D2 and D3, as well as the role of UVB in producing D3. 🌞 It’s fascinating how the body transforms sunlight into something so crucial for our bones and immune system. 💡 This video has added to my understanding and given me a few new insights—thank you for making it so easy to follow! 🙌
Not the Buffalo Bill meme😂 I’m a big vit D consumer. 8000 iu’s in the winter. Living in Saskatchewan is hard enough in the winter
Search Dr. Campbell re calcifediol monohydrate. If having emergency surgery, and you have not been taking your vitamin d, this form may save your life or prevent a serious bfecton surgery.
Hi , why do we get high level of 125 hydroxy vit D without zero supplements ? What could be the reason. My daughter who is 8 year old have 130 125 hydroxy vit D without any supplements.
When he said "sunscreennis good for your skin" i knew he didnt know what he was talking about and left
This video is only confusing, 1000ui of vitamin you take may be enough if according to YOUR tests YOUR vitamin d is normal, BUT most people have very low vitamin levels of about 20, and in this case 1000 ui is of no use, it will take a much higher dose i.e. from 6000/10000 per day .
It is ALWAYS necessary to do tests before taking vitamin D, you cannot generalize as you did!
ONLY after D3 examinations ( Witamine D-25(OH)D) everyone will be able to figure out the right dose.
Also it's always advisable to take k2-mk7 especially if you take above 4000ui a day.
After 6 months, D3 tests should be repeated. and if the values are good, stabilization is done by continuing to take at least 2000ui.
I am sorry that as a doctor you did not give these clear directions.
I wonder how you have over a million members!
Please mention the poison chemicals in the sunscreen…And how it adds to the sickness we already have in this country and the World…
Cant doctors have any other name??
In the UK I believe that milk is NOT fortified.